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1

Advances in the therapy of Alzheimer’s disease: targeting amyloid beta and tau and perspectives for the future

Hampel, Harald, Schneider, Lon S, Giacobini, Ezio, Kivipelto, Miia, Sindi, Shireen, Dubois, Bruno, Broich, Karl, Nisticò, Robert, Aisen, Paul S, Lista, Simone

Journal:

Expert Review of Neurotherapeutics

Year:

2015

Language:

english

File:

PDF, 818 KB

english, 2015

2

Pyruvate, Glutamate and Tricarboxylic Acid Intermediates in the Crustacean Stretch Receptor Neurone after Prolonged Impulse Activity

Ezio Giacobini, Pier Carlo Marchisio

Journal:

Acta Physiologica

Year:

1966

Language:

english

File:

PDF, 146 KB

english, 1966

3

Nicotine, Parkinson's and Alzheimer's Disease

Smith, Carrl J., Giacobini, Ezio

Journal:

Reviews in the Neurosciences

Year:

1992

Language:

english

File:

PDF, 4.08 MB

english, 1992

4

Cerebrospinal fluid choline levels are decreased in Parkinson's disease

Bala V. Manyam, Ezio Giacobini, Jerry A. Colliver

Journal:

Annals of Neurology

Year:

1990

Language:

english

File:

PDF, 295 KB

english, 1990

5

3H-thymidine long survival autoradiography as a method for dating the time of neuronal origin in the chick embryo: The locus coeruleus and cerebellar Purkinje cells

Lorraine Yurkewicz, Jean M. Lauder, Mario Marchi, Ezio Giacobini

Journal:

The Journal of Comparative Neurology

Year:

1981

Language:

english

File:

PDF, 1.04 MB

english, 1981

6

Mechanisms of cholinesterase inhibition in senile dementia of the alzheimer type: Clinical, pharmacological, and therapeutic aspects

Robert E. Becker, Ezio Giacobini

Journal:

Drug Development Research

Year:

1988

Language:

english

File:

PDF, 2.10 MB

english, 1988

7

Pharmacokinetics and pharmacodynamics of acetylcholinesterase inhibition: Can acetylcholine levels in the brain be improved in alzheimer's disease?

Robert E. Becker, Ezio Giacobini

Journal:

Drug Development Research

Year:

1988

Language:

english

File:

PDF, 752 KB

english, 1988

8

Effects of metrifonate, a long-acting cholinesterease inhibitor, in alzheimer disease: Report of an open trial

Robert E. Becker, Jerry Colliver, Rodger Elble, Eleanor Feldman, Ezio Giacobini, Vinod Kumar, Stephen Markwell, Pamela Morieatry, Randolph Parks, Samuel D. Schillcutt, Latha Unni, Sandra Vicari, Cindy

Journal:

Drug Development Research

Year:

1990

Language:

english

File:

PDF, 680 KB

english, 1990

9

Effects of nicotine on levels of acetylcholine and biogenic amines in rat cortex

Kathleen L. Summers, Gabriel Cuadra, Dean Naritoku, Ezio Giacobini

Journal:

Drug Development Research

Year:

1994

Language:

english

File:

PDF, 959 KB

english, 1994

10

Cholinergic function and Alzheimer's disease

Journal:

International Journal of Geriatric Psychiatry

Year:

2003

Language:

english

File:

PDF, 131 KB

english, 2003

11

Neuronal control of neurotransmitters biosynthesis during development

Journal:

Journal of Neuroscience Research

Year:

1975

Language:

english

File:

PDF, 1.04 MB

english, 1975

12

Acetylcholinesterase activity in ventricular and cisternal csf of dogs: Effect of chlorpromazine

Silvio R. Bareggi, Ezio Giacobini

Journal:

Journal of Neuroscience Research

Year:

1978

Language:

english

File:

PDF, 336 KB

english, 1978

13

Development and aging of noradrenergic cell bodies and axon terminals in the chicken

Dr. Lorraine Yurkewicz, Mario Marchi, Jean M. Lauder, Ezio Giacobini

Journal:

Journal of Neuroscience Research

Year:

1981

Language:

english

File:

PDF, 1.93 MB

english, 1981

14

Identification and characterization of pipecolic acid binding sites in mouse brain

Maria D. C. Gutierrez, Ezio Giacobini

Journal:

Neurochemical Research

Year:

1985

Language:

english

File:

PDF, 557 KB

english, 1985

15

Quantitative determination and regional distribution of pipecolic acid in rodent brain

Jang Soo Kim, Ezio Giacobini

Journal:

Neurochemical Research

Year:

1984

Language:

english

File:

PDF, 549 KB

english, 1984

16

Transport of pipecolic acid in adult and developing mouse brain

Jang Soo Kim, Ezio Giacobini

Journal:

Neurochemical Research

Year:

1985

Language:

english

File:

PDF, 560 KB

english, 1985

17

Relation of brain regional physostigmine concentration to cholinesterase activity and acetylcholine and choline levels in rat

Marta Hallak, Ezio Giacobini

Journal:

Neurochemical Research

Year:

1986

Language:

english

File:

PDF, 576 KB

english, 1986

18

Time course of appearance ofα-bungarotoxin binding sites during development of chick ciliary ganglion and iris

Vincent A. Chiappinelli, Ezio Giacobini

Journal:

Neurochemical Research

Year:

1978

Language:

english

File:

PDF, 644 KB

english, 1978

19

Preferential inhibition of acetylcholinesterase molecular forms in rat brain

Nobuo Ogane, Ezio Giacobini, Erik Messamore

Journal:

Neurochemical Research

Year:

1992

Language:

english

File:

PDF, 585 KB

english, 1992

20

Metrifonate effects on acetylcholine and biogenic amines in rat cortex

Francesca Mori, Gabriel Cuadra, Ezio Giacobini

Journal:

Neurochemical Research

Year:

1995

Language:

english

File:

PDF, 745 KB

english, 1995

21

5-Fluoronicotine, noranhydroecgonine, and pyridyl-methylpyrrolidine release acetylcholine and biogenic amines in rat cortex in vivo

Kathleen L. Summers, Patrick Lippiello, Steven Verhulst, Ezio Giacobini

Journal:

Neurochemical Research

Year:

1995

Language:

english

File:

PDF, 585 KB

english, 1995

22

A microdialysis study of the effects of the nicotinic agonist RJR-2403 on cortical release of acetylcholine and biogenic amines

Kathleen L. Summers, Patrick Lippiello, Ezio Giacobini

Journal:

Neurochemical Research

Year:

1996

Language:

english

File:

PDF, 553 KB

english, 1996

23

Davide Schiffer: Attraverso il Microscopio

Journal:

Neurological Sciences

Year:

2011

Language:

english

File:

PDF, 71 KB

english, 2011

24

QUANTITATIVE DETERMINATION OF CHOLINESTERASE IN INDIVIDUAL SYMPATHETIC CELLS

Journal:

Journal of Neurochemistry

Year:

1957

Language:

english

File:

PDF, 797 KB

english, 1957

25

A CYTOCHEMICAL STUDY OF THE LOCALIZATION OF CARBONIC ANHYDRASE IN THE NERVOUS SYSTEM

Journal:

Journal of Neurochemistry

Year:

1962

Language:

english

File:

PDF, 548 KB

english, 1962

26

Metrifonate: A Cholinesterase Inhibitor for Alzheimer's Disease Therapy

Lon S. Schneider, Ezio Giacobini

Journal:

CNS Drug Reviews

Year:

1999

Language:

english

File:

PDF, 130 KB

english, 1999

27

Highlights from the Sixth International Stockholm/Springfield Meeting on Advances in Alzheimer Therapy Stockholm, Sweden, April 5–8, 2000

Journal:

CNS Drug Reviews

Year:

2000

Language:

english

File:

PDF, 74 KB

english, 2000

28

Cholinesterase Inhibitors Stabilize Alzheimer's Disease

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 949 KB

english, 2000

29

Quantitative Determination of Acetylcholinesterase Activity in Individual Nerve Cells

GIACOBINI, EZIO, ZAJICEK, JOSEPH

Journal:

Year:

1956

File:

PDF, 197 KB

1956

30

Cholinesterase Inhibitors Stabilize Alzheimer Disease

Journal:

Neurochemical Research

Year:

2000

Language:

english

File:

PDF, 35 KB

english, 2000

31

Cholinesterases: New Roles in Brain Function and in Alzheimer's Disease

Journal:

Neurochemical Research

Year:

2003

Language:

english

File:

PDF, 54 KB

english, 2003

32

Energy metabolism and ion transport studied in single neurons

Journal:

Year:

1967

Language:

english

File:

PDF, 337 KB

english, 1967

33

Therapy for Alzheimer's disease

Journal:

Molecular Neurobiology

Year:

1994

Language:

english

File:

PDF, 229 KB

english, 1994

34

L-β-methylamino-alanine-induced behavioral changes in rats

Yutaka Matsuoka, Rakonczay Zoltan, Giacobini Ezio, Naritoku Dean

Journal:

Pharmacology Biochemistry and Behavior

Year:

1993

Language:

english

File:

PDF, 616 KB

english, 1993

35

Aging, Alzheimer’s disease, and estrogen therapy

Journal:

Experimental Gerontology

Year:

1998

Language:

english

File:

PDF, 57 KB

english, 1998

36

Cholinergic foundations of Alzheimer's disease therapy

Journal:

Journal of Physiology-Paris

Year:

1998

Language:

english

File:

PDF, 434 KB

english, 1998

37

Cholinesterase in Muscles: A Histochemical and Microgasornetric Study

Ezio Giacobini, Bo Holmstedt

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1960

Language:

english

File:

PDF, 767 KB

english, 1960

38

Histochemical Demonstration of AChE Activity in Isolated Nerve Cells

Journal:

Acta Physiologica

Year:

1956

Language:

english

File:

PDF, 2.17 MB

english, 1956

39

Determination of ‘Cholinesterme in the Cellular Components of Neurones

Journal:

Acta Physiologica

Year:

1959

Language:

english

File:

PDF, 1.45 MB

english, 1959

40

Quantitative Determination of Cholinesterase in Individual Spinal Ganglion Cells

Journal:

Acta Physiologica

Year:

1959

Language:

english

File:

PDF, 1.10 MB

english, 1959

41

Variations of Glycolytic Intermediates, Phosphate Compounds and Pyridine Nucleotides after Prolonged Stimulation of an Isolated Crustacean Neurone

Ezio Giacobini, Alfonso Grasso

Journal:

Acta Physiologica

Year:

1966

Language:

english

File:

PDF, 472 KB

english, 1966

42

The Action of Tricarboxylic Acid Cycle Intermediates and Glutamate on the Impulse Activity and Respiration of the Crayfish Stretch Receptor Neurone

Ezio Giacobini, Pier Carlo Marchisio

Journal:

Acta Physiologica

Year:

1966

Language:

english

File:

PDF, 529 KB

english, 1966

43

Cholinesterase Activity in Innervated and Denervated Sympathetic Ganglion Cells of the Cat

Ezio Giacobini, Bo Palmborg, Folke Sjöqvist

Journal:

Acta Physiologica

Year:

1967

Language:

english

File:

PDF, 1.15 MB

english, 1967

44

Intracellular Variations of Na and K in Isolated Nerve Cells

Ezio Giacobini, Stefan Hovmark, Zurab Kometiani

Journal:

Acta Physiologica

Year:

1967

Language:

english

File:

PDF, 543 KB

english, 1967

45

Pentose Shunt Enzymes in the Crustacean Stretch Receptor Neuron after Impulse Activity

Ezio Giacobini, Johan F. Jongkind

Journal:

Acta Physiologica

Year:

1968

Language:

english

File:

PDF, 140 KB

english, 1968

46

Monoamine Oxidase in Sympathetic Ganglia of the Cat

Silvana Consolo, Ezio Giacobini, Kristian Karjalainen

Journal:

Acta Physiologica

Year:

1968

Language:

english

File:

PDF, 429 KB

english, 1968

47

Use of microgasometric techniques in pharmacological studies

Journal:

Biochemical Pharmacology

Year:

1962

Language:

english

File:

PDF, 716 KB

english, 1962

48

Differential inhibition of acetylcholinesterase molecular forms in normal and Alzheimer disease brain

Nobuo Ogane, Ezio Giacobini, Robert Struble

Journal:

Year:

1992

Language:

english

File:

PDF, 656 KB

english, 1992

49

Effect of MDL 73,745 on acetylcholine and biogenic amine levels in rat cortex

Xiao-dong Zhu, Ezio Giacobini, Jean-Marie Hornsperger

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 615 KB

english, 1995

50

Cholinesterase inhibitor effects on extracellular acetylcholine in rat cortex

Erik Messamore, Ulrika Warpman, Nobuo Ogane, Ezio Giacobini

Journal:

Neuropharmacology

Year:

1993

Language:

english

File:

PDF, 481 KB

english, 1993